Pediatric Neuroradiology, G. Gaslini Children's Research Hospital, Largo G Gaslini 5, Genova 16147, Italy.
Pediatr Radiol. 2010 Jun;40(6):999-1009. doi: 10.1007/s00247-010-1613-y. Epub 2010 Apr 30.
While MRI has been instrumental in significantly improving care in children harbouring brain tumours, conventional sequences lack information regarding functional parameters including cellularity, haemodynamics and metabolism. Advanced MR imaging modalities, such as diffusion (including diffusion tensor imaging and fibre tractography), perfusion and spectroscopy have significantly improved our understanding of the physiopathology of brain tumours and have provided invaluable additional information for treatment planning and monitoring of treatment results. The contribution of these methods to the characterization of brain neoplasms in children is the focus of the present manuscript.
虽然 MRI 在显著改善脑瘤患儿的治疗方面发挥了重要作用,但常规序列缺乏有关功能参数的信息,包括细胞密度、血液动力学和代谢。先进的磁共振成像方式,如扩散(包括扩散张量成像和纤维束追踪)、灌注和光谱,极大地提高了我们对脑瘤病理生理学的认识,并为治疗计划和监测治疗结果提供了宝贵的额外信息。本文重点介绍了这些方法在儿童脑肿瘤特征描述中的作用。