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肾脏恶性肿瘤:影像学策略。

Malignant tumours of the kidney: imaging strategy.

机构信息

Department of Radiology G1, Academic Medical Center, PO Box 22700, Amsterdam 1100 DE, The Netherlands.

出版信息

Pediatr Radiol. 2010 Jun;40(6):1010-8. doi: 10.1007/s00247-010-1584-z. Epub 2010 Apr 30.

Abstract

Primitive malignant renal tumours comprise 6% of all childhood cancers. Wilms tumour (WT) or nephroblastoma is the most frequent type accounting for more than 90%. Imaging alone cannot differentiate between these tumours with certainty but it plays an important role in screening, diagnostic workup, assessment of therapy response, preoperative evaluation and follow-up. The outcome of WT after therapy is excellent with an overall survival around 90%. In tumours such as those where the outcome is extremely good, focus can be shifted to a risk-based stratification to maintain excellent outcome in children with low risk tumours while improving quality of life and decreasing toxicity and costs. This review will discuss the imaging issues for WT from the European perspective and briefly discuss the characteristics of other malignant renal tumours occurring in children and new imaging techniques with potential in this matter.

摘要

原始恶性肾肿瘤占儿童所有癌症的 6%。Wilms 瘤(WT)或肾母细胞瘤是最常见的类型,占比超过 90%。仅凭影像学检查无法明确区分这些肿瘤,但它在筛查、诊断评估、治疗反应评估、术前评估和随访中发挥着重要作用。WT 经过治疗后的预后极好,总生存率约为 90%。在预后极好的肿瘤中,可以将重点转移到基于风险的分层上,以在维持低危肿瘤患儿的优异治疗效果的同时,提高生活质量并降低毒性和成本。本文将从欧洲视角探讨 WT 的影像学问题,并简要讨论儿童中发生的其他恶性肾肿瘤的特征以及在该领域具有潜力的新技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1065/2861760/102b209aa890/247_2010_1584_Fig1_HTML.jpg

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