Trampuz A, Steinrücken J, Clauss M, Bizzini A, Furustrand U, Uçkay I, Peter R, Bille J, Borens O
Service des maladies infectieuses, Département de médecine interne , CHUV, 1011 Lausanne.
Rev Med Suisse. 2010 Apr 7;6(243):731-4.
For successful treatment of prosthetic joint infection, the identification of the infecting microorganism is crucial. Cultures of synovial fluid and intraoperative periprosthetic tissue represent the standard method for diagnosing prosthetic joint infection. Rapid and accurate diagnostic tools which can detect a broad range of causing microorganisms and their antimicrobial resistance are increasingly needed. With newer diagnostic techniques, such as sonication of removed implants, microcalorimetry, molecular methods and mass spectrometry, the sensitivity has been significantly increased. In this article, we describe the conventional and newer diagnostic techniques with their advantages and potential future applications.
对于人工关节感染的成功治疗，识别感染微生物至关重要。滑液和术中假体周围组织培养是诊断人工关节感染的标准方法。越来越需要能够检测多种致病微生物及其抗菌耐药性的快速准确诊断工具。随着诸如取出植入物的超声处理、微量量热法、分子方法和质谱等更新的诊断技术出现，灵敏度已显著提高。在本文中，我们描述了传统和更新的诊断技术及其优点和潜在的未来应用。
