Section of Cardiac Electrophysiology, Division of Cardiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Cardiovasc Ther. 2010 Oct;28(5):255-63. doi: 10.1111/j.1755-5922.2010.00147.x.
Patients with structural heart disease and ventricular tachycardia (VT) can be difficult to manage clinically. Many treatment options are available, but no single approach can be applied to every patient. This review aims to discuss the current options available for the management of this population. VT can be associated with cardiomyopathy of any etiology, both ischemic and nonischemic. Antiarrhythmic drugs have not been shown to decrease mortality in this patient population, but they can help reduce episodes. While the advent of the implantable cardioverter-defibrillator has revolutionized the treatment of VT, patients with recurrent shocks for VT have high morbidity and mortality. The development of catheter ablation over the past few decades has greatly aided the ability to control VT in these patients. The approach to patients with VT and structural heart disease is multifaceted. Often, a combination of therapeutic techniques is required to obtain the best result.
患有结构性心脏病和室性心动过速 (VT) 的患者在临床上可能难以治疗。有许多治疗选择,但没有单一的方法可以应用于每个患者。本综述旨在讨论目前可用于管理该人群的选择。VT 可与任何病因的心肌病相关,包括缺血性和非缺血性心肌病。抗心律失常药物并未显示可降低该患者人群的死亡率,但它们可以帮助减少发作次数。虽然植入式心脏复律除颤器的出现彻底改变了 VT 的治疗方法,但因 VT 反复发作而接受电击的患者发病率和死亡率很高。过去几十年中导管消融技术的发展极大地提高了控制这些患者 VT 的能力。患有 VT 和结构性心脏病的患者的治疗方法是多方面的。通常,需要结合多种治疗技术才能获得最佳效果。