Department of Mathematics, Dowling College, Idle Hour Blvd, Oakdale, NY 11769, USA.
J Hazard Mater. 2010 Aug 15;180(1-3):212-6. doi: 10.1016/j.jhazmat.2010.04.016. Epub 2010 Apr 13.
Copper nanoparticles are used in wide variety of applications and in the current study we report the antimicrobial activity of these particles. Influence of pH, temperature, aeration rate, concentration of nanoparticles and concentration of bacteria on the toxicity of copper nanoparticles against Escherichia coli have been studied using a centroid mixture design of experiment. The linear and quadratic regression model shows that the toxicity of copper nanoparticles not only depends on the primary effect of the parameters tested (pH, temperature, aeration, concentration of E. coli and concentration of nanoparticles), but also on the interactive effect of these parameters.
铜纳米粒子在各种应用中被广泛使用，在本研究中，我们报告了这些粒子的抗菌活性。使用中心点混合物实验设计研究了 pH 值、温度、通气率、纳米粒子浓度和细菌浓度对铜纳米粒子对大肠杆菌毒性的影响。线性和二次回归模型表明，铜纳米粒子的毒性不仅取决于所测试参数（pH 值、温度、通气、大肠杆菌浓度和纳米粒子浓度）的主要影响，还取决于这些参数的相互作用。
