Department of Anaesthesia 3, Hôpital Pellegrin, Centre Hospitalo-Universitaire Bordeaux, 33076 Bordeaux, France.
Anesth Analg. 2010 Jun 1;110(6):1676-9. doi: 10.1213/ANE.0b013e3181d8a14c. Epub 2010 Apr 30.
In this study, we sought to determine the level of inspiratory pressures allowing adequate and safe ventilation without any risk of gastric insufflation (GI) in children according to age.
One hundred children, aged 1 day to 16 years, ASA physical status I to II, scheduled for general anesthesia were studied prospectively. After induction of anesthesia, children's lungs were ventilated with pressure-controlled ventilation. The initial inspiratory pressure was 10 cm H(2)O and was increased by steps of 5 cm H(2)O, up to a maximum of 25 cm H(2)O. At each step, GI was detected by epigastric auscultation. The recorded data were age and weight. At each step, the inspiratory pressure, the respiratory rate, the expired tidal volume, the minute ventilation, and the occurrence of GI were also recorded.
GI occurred in 78 children. GI occurred in 95% of children younger than 1 year, in 93% of children aged 1 to 5 years, and 56% of children older than 5 years (P = 0.001). The pressure threshold at which GI occurred increased with age: the younger the child, the lower the GI pressure threshold. Tidal volume increased with inspiratory pressure, but at >15 cm H(2)O, tidal volume did not change significantly.
The inspiratory pressure threshold at which GI can occur depends on age. It is low in infants and increases with age. In most cases, proper ventilation without GI was obtained with an inspiratory pressure </=15 cm H(2)O. Increasing inspiratory pressure above this threshold results in an increase in GI and no change in tidal volume.
在这项研究中,我们旨在根据年龄确定吸气压力水平,以在儿童中实现充足且安全的通气而无胃充气(GI)风险。
100 名年龄在 1 天至 16 岁、ASA 身体状况 I 至 II 级、计划全身麻醉的儿童前瞻性研究。麻醉诱导后,使用压力控制通气对儿童的肺部进行通气。初始吸气压力为 10 cm H2O,并以 5 cm H2O 的步长增加,最高可达 25 cm H2O。在每个步骤中,通过上腹部听诊检测 GI。记录的数据为年龄和体重。在每个步骤中,还记录了吸气压力、呼吸频率、呼气潮气量、分钟通气量和 GI 的发生情况。
78 名儿童发生 GI。1 岁以下儿童 GI 发生率为 95%,1 至 5 岁儿童为 93%,5 岁以上儿童为 56%(P = 0.001)。发生 GI 的压力阈值随年龄增加而增加:儿童越小,GI 压力阈值越低。潮气量随吸气压力增加而增加,但在 >15 cm H2O 时,潮气量无明显变化。
发生 GI 的吸气压力阈值取决于年龄。在婴儿中较低,并随年龄增加而增加。在大多数情况下,吸气压力 <=15 cm H2O 即可获得适当的通气而无 GI。超过此阈值增加吸气压力会导致 GI 增加而潮气量无变化。