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慢性阻塞性肺疾病(COPD)高风险人群的特征分析

Characterisation of a population at increased risk of COPD.

作者信息

Soares Sandra, Costa Isabel, Neves Ana Luísa, Couto Luciana

机构信息

Internato Médico de Medicina Geral e Familiar/Resident, General Practice.

出版信息

Rev Port Pneumol. 2010 Mar-Apr;16(2):237-52.

Abstract

INTRODUCTION

Smoking is the main risk factor for COPD, and it is estimated that 15-20% of smokers will develop the pathology. Characterising this risk population is an important step in improved diagnosis of COPD, an increasing primary care challenge.

AIMS

To determine the percentage of smokers identified in patients aged 45-65 years old in a health centre, and their characterisation; to determine possible relationships between respiratory symptoms and abnormal obstruction of the small airways and the other variables studied.

MATERIAL AND METHODS

Observational, analytical, cross-sectional study carried out in a Portuguese health centre.

POPULATION

smokers aged 45-65 years old who filled in a questionnaire and underwent spirometry. Statistical analysis was performed with SPSS v.13.0 (level of significance 0.05).

RESULTS

The sample was composed of 157 participants (31% men and 69% womens); average age 53.85 years; average age at start of smoking 16.64 years; average tobacco consumption 37.78 pack-years. Respiratory symptoms were present in 68.8% of the individuals, and were more frequent in men, those who started smoking earlier and those with higher tobacco consumption (p<0.05). Thirty percent had abnormal obstruction of the small airways, with this more frequent in older smokers and those with heavier tobacco consumption (p<0.05).

DISCUSSION AND CONCLUSIONS

The underdiagnosis of smoking raises awareness of the importance of identifying this risk population and the need to implement preventative measures. These, in tandem with a better characterisation of this population, may contribute to the improved diagnosis and management of COPD.

摘要

引言

吸烟是慢性阻塞性肺疾病(COPD)的主要风险因素,据估计15%-20%的吸烟者会患上这种疾病。确定这一风险人群是改善COPD诊断的重要一步,而COPD在初级医疗保健中带来的挑战日益增加。

目的

确定在一家健康中心45-65岁患者中吸烟者的比例及其特征;确定呼吸道症状与小气道异常阻塞以及其他研究变量之间可能存在的关系。

材料与方法

在一家葡萄牙健康中心开展的观察性、分析性横断面研究。

研究对象

年龄在45-65岁之间填写了问卷并接受肺功能测定的吸烟者。使用SPSS v.13.0进行统计分析(显著性水平为0.05)。

结果

样本由157名参与者组成(男性占31%,女性占69%);平均年龄53.85岁;开始吸烟的平均年龄16.64岁;平均吸烟量为37.78包年。68.8%的个体有呼吸道症状,在男性、开始吸烟较早者和吸烟量较高者中更常见(p<0.05)。30%的人存在小气道异常阻塞,在年龄较大的吸烟者和吸烟量较大者中更常见(p<0.05)。

讨论与结论

吸烟的诊断不足提高了对识别这一风险人群重要性的认识,以及实施预防措施的必要性。这些措施,再加上对这一人群更好的特征描述,可能有助于改善COPD的诊断和管理。

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