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移植术后入院高血糖与住院时间的关系。

Association between admission hyperglycemia and length of stay after renal transplantation.

机构信息

Department of Internal Medicine, University of Florida, Gainesville, Florida 32610-0226, USA.

出版信息

Endocr Pract. 2010 Sep-Oct;16(5):805-9. doi: 10.4158/EP09290.OR.

Abstract

OBJECTIVE

To compare length of stay, readmissions, infections, and mortality in patients with end-stage renal disease who have been admitted to receive renal transplant, stratified according to diabetes status and admission glucose concentration.

METHODS

We conducted a retrospective analysis of all adult patients who underwent renal transplant at an academic center during 2006. Patients were stratified according to diabetes status before transplant and glucose concentration at hospital admission (hyperglycemic [> 180 mg/dL] or normoglycemic [≤ = 180 mg/dL]). The groups were compared with respect to length of stay, number of readmissions during the 2-year period after transplant, infections, and mortality.

RESULTS

Ninety-eight patients underwent renal transplant during the study period, and 11 were excluded because of incomplete data. Thus, 87 patients were included. There was a trend towards greater length of stay and higher mortality in patients with known diagnosis of diabetes. When stratified according to glucose concentration at admission, patients with hyperglycemia had a significantly longer length of stay than normoglycemic patients (10 ± 4.3 days vs 7.9 ± 2.9; P = .039), even after correcting for diabetes status.

CONCLUSION

Hyperglycemia at hospital admission, rather than a known diagnosis of diabetes, is associated with increased length of stay in patients admitted for renal transplant.

摘要

目的

比较根据糖尿病状态和入院时血糖浓度分层的终末期肾病患者接受肾移植的住院时间、再入院率、感染和死亡率。

方法

我们对 2006 年在学术中心接受肾移植的所有成年患者进行了回顾性分析。患者根据移植前的糖尿病状态和入院时的血糖浓度(高血糖[>180mg/dL]或正常血糖[≤=180mg/dL])进行分层。比较两组的住院时间、移植后 2 年内的再入院次数、感染和死亡率。

结果

研究期间有 98 名患者接受了肾移植,有 11 名患者因数据不完整而被排除。因此,共有 87 名患者被纳入研究。已知患有糖尿病的患者住院时间较长,死亡率较高。按入院时血糖浓度分层,高血糖患者的住院时间明显长于正常血糖患者(10±4.3 天 vs 7.9±2.9 天;P=0.039),即使校正了糖尿病状态。

结论

与已知的糖尿病诊断相比,入院时的高血糖与接受肾移植的患者住院时间延长有关。

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