Hospital for Sick Children, Toronto, Ontario, Canada.
J Bone Joint Surg Am. 2010 May;92(5):1122-9. doi: 10.2106/JBJS.H.01735.
The optimal management of femoral fractures in adolescents is controversial. This study was performed to compare the results and complications of four methods of fixation and to determine the factors related to those complications.
We conducted a retrospective cohort study of 194 diaphyseal femoral fractures in 189 children and adolescents treated with elastic stable intramedullary nail fixation, external fixation, rigid intramedullary nail fixation, or plate fixation. After adjustment for age, weight, energy of the injury, polytrauma, fracture level and pattern, and extent of comminution, treatment outcomes were compared in terms of the length of the hospital stay, time to union, and complication rates, including loss of reduction requiring a reoperation, malunion, nonunion, refracture, infection, and the need for a reoperation other than routine hardware removal.
The mean age of the patients was 13.2 years, and their mean weight was 49.5 kg. There was a loss of reduction of two of 105 fractures treated with elastic nail fixation and ten of thirty-three treated with external fixation (p < 0.001). At the time of final follow-up, five patients (two treated with external fixation and one in each of the other groups) had >or=2.0 cm of shortening. Eight of the 104 patients (105 fractures) treated with elastic nail fixation underwent a reoperation (two each because of loss of reduction, refracture, the need for trimming or advancement of the nail, and delayed union or nonunion). Sixteen patients treated with external fixation required a reoperation (ten because of loss of reduction, one for replacement of a pin complicated by infection, one for débridement of the site of a deep infection, three because of refracture, and one for lengthening). One patient treated with a rigid intramedullary nail required débridement at the site of a deep infection, and one underwent removal of a prominent distal interlocking screw. One fracture treated with plate fixation required refixation following refractures. A multivariate analysis with adjustment for baseline differences showed external fixation to be associated with a 12.41-times (95% confidence interval = 2.26 to 68.31) greater risk of loss of reduction and/or malunion than elastic stable intramedullary nail fixation.
External fixation was associated with the highest rate of complications in our series of adolescents treated for a femoral fracture. Although the other three methods yielded comparable outcomes, we cannot currently recommend one method of fixation for all adolescents with a femoral fracture. The choice of fixation will remain influenced by surgeon preference based on expertise and experience, patient and fracture characteristics, and patient and family preferences.
青少年股骨骨折的最佳治疗方法存在争议。本研究旨在比较四种固定方法的治疗效果和并发症,并确定与这些并发症相关的因素。
我们对 189 名儿童和青少年的 194 例股骨干骨折进行了回顾性队列研究,这些患者分别接受弹性稳定髓内钉固定、外固定、刚性髓内钉固定或钢板固定。在调整年龄、体重、损伤能量、多发伤、骨折部位和类型、粉碎程度后,比较住院时间、愈合时间和并发症发生率,包括需要再次手术的复位丢失、畸形愈合、不愈合、再骨折、感染以及除常规内固定取出外需要再次手术的发生率。
患者的平均年龄为 13.2 岁,平均体重为 49.5kg。105 例弹性钉固定治疗的骨折中有 2 例和 33 例外固定治疗的骨折中有 10 例发生复位丢失(p<0.001)。最终随访时,5 例(2 例外固定治疗,1 例其他组)存在>2.0cm 的短缩。104 例弹性钉固定治疗的患者中有 8 例(105 例骨折)需要再次手术(2 例因复位丢失、再骨折、需要修整或推进钉、延迟愈合或不愈合而手术,2 例因需要去除突出的远端锁定螺钉而手术)。16 例外固定治疗的患者需要再次手术(10 例因复位丢失、1 例因感染导致的钉更换、1 例因深部感染部位清创、3 例因再骨折、1 例因延长而手术)。1 例刚性髓内钉固定治疗的患者因深部感染部位需要清创,1 例因突出的远端锁定螺钉需要去除。1 例钢板固定治疗的骨折因再骨折需要重新固定。多变量分析调整基线差异后显示,与弹性稳定髓内钉固定相比,外固定与复位丢失和/或畸形愈合的风险增加 12.41 倍(95%置信区间=2.26 至 68.31)。
在我们治疗的青少年股骨骨折系列中,外固定的并发症发生率最高。尽管其他三种方法的治疗效果相当,但目前我们不能推荐一种固定方法适用于所有青少年股骨骨折患者。固定方法的选择仍将受到医生专业知识和经验、患者和骨折特征以及患者和家属偏好的影响。