Department of Emergency Medicine, Yonsei University College of Medicine, Seoul, Korea.
Emerg Med J. 2010 May;27(5):409-10. doi: 10.1136/emj.2009.084277.
Methanol is generally known to cause visual impairment and various systemic manifestations. There are a few reported specific findings for methanol intoxication on magnetic resonance imaging (MRI) of the brain. A case is reported of unilateral blindness with third cranial nerve palsy oculus sinister (OS) after the ingestion of methanol. Unilateral damage of the retina and optic nerve were confirmed by fundoscopy, flourescein angiography, visual evoked potential and electroretinogram. The optic nerve and extraocular muscles (superior rectus, medial rectus, inferior rectus and inferior oblique muscle) were enhanced by gadolinium-DTPA on MRI of the orbit. This is the first case report of permanent monocular blindness with confirmed unilateral damage of the retina and optic nerve, combined with third cranial nerve palsy after methanol ingestion.
甲醇通常会导致视力损害和各种全身表现。有一些关于甲醇中毒的磁共振成像（MRI）的特定发现。报告了一例在摄入甲醇后出现单侧失明伴第三颅神经麻痹左眼（OS）。眼底镜检查、荧光血管造影、视觉诱发电位和视网膜电图证实单侧视网膜和视神经损伤。眼眶 MRI 显示视神经和眼外肌（上直肌、内直肌、下直肌和下斜肌）增强。这是首例甲醇摄入后永久性单眼失明伴单侧视网膜和视神经损伤合并第三颅神经麻痹的病例报告。
