Belardinelli E, Cavalcanti S
Department of Electronics, Computer Science and Systems, University of Bologna, Italy.
Comput Biol Med. 1991;21(1-2):1-13. doi: 10.1016/0010-4825(91)90030-d.
An original mathematical model for the local study of blood motion in tapered and distensible arteries was developed. The theory takes into account the nonlinear terms of the Navier-Stokes equations, as well as wall motion and instantaneous taper angle, and allows the calculation of axial and radial velocity profiles with low computational complexity. The relationship between instantaneous flow and the pressure gradient in steady and dynamic conditions is evaluated by means of the mathematical model. The results obtained by simulation agree with experimental evidence and also indicate that the anatomic tapering of arteries and pulsatile changes in diameter highly influence blood motion.
建立了一个用于局部研究锥形可扩张动脉中血液流动的原始数学模型。该理论考虑了纳维-斯托克斯方程的非线性项,以及血管壁运动和瞬时锥角,并能够以较低的计算复杂度计算轴向和径向速度分布。通过该数学模型评估了稳态和动态条件下瞬时流量与压力梯度之间的关系。模拟得到的结果与实验证据相符,并且还表明动脉的解剖学锥形和直径的脉动变化对血液流动有很大影响。