Division of General Internal Medicine, Department of Medicine, The Johns Hopkins University, Baltimore, Maryland, USA.
Popul Health Manag. 2010 Aug;13(4):201-7. doi: 10.1089/pop.2009.0051.
Obesity is underdiagnosed, hampering system-based health promotion and research. Our objective was to develop and validate a claims-based risk model to identify obese persons using medical diagnosis and prescription records. We conducted a cross-sectional analysis of de-identified claims data from enrollees of 3 Blue Cross Blue Shield plans who completed a health risk assessment capturing height and weight. The final sample of 71,057 enrollees was randomly split into 2 subsamples for development and validation of the obesity risk model. Using the Johns Hopkins Adjusted Clinical Groups case-mix/predictive risk methodology, we categorized study members' diagnosis (ICD) codes. Logistic regression was used to determine which claims-based risk markers were associated with a body mass index (BMI) > or = 35 kg/m(2). The sensitivities of the scores > or =90(th) percentile to detect obesity were 26% to 33%, while the specificities were >90%. The areas under the receiver operator curve ranged from 0.67 to 0.73. In contrast, a diagnosis of obesity or an obesity medication alone had very poor sensitivity (10% and 1%, respectively); the obesity risk model identified an additional 22% of obese members. Varying the percentile cut-point from the 70(th) to the 99(th) percentile resulted in positive predictive values ranging from 15.5 to 59.2. An obesity risk score was highly specific for detecting a BMI > or = 35 kg/m(2) and substantially increased the detection of obese members beyond a provider-coded obesity diagnosis or medication claim. This model could be used for obesity care management and health promotion or for obesity-related research.
肥胖症的诊断率较低,这阻碍了以系统为基础的健康促进和研究。我们的目标是开发和验证一种基于索赔的风险模型,以使用医疗诊断和处方记录来识别肥胖患者。我们对参加了健康风险评估(其中包括身高和体重)的 3 个蓝十字蓝盾计划的参保者的匿名索赔数据进行了横断面分析。最终的 71057 名参保者样本被随机分为 2 个子样本,用于开发和验证肥胖风险模型。使用约翰霍普金斯调整临床分组病例组合/预测风险方法,我们对研究对象的诊断(ICD)代码进行分类。逻辑回归用于确定哪些基于索赔的风险标志物与 BMI≥35kg/m2相关。分数≥第 90 个百分位数的灵敏度为 26%至 33%,而特异性>90%。接收者操作曲线下的面积范围为 0.67 至 0.73。相比之下,肥胖诊断或单独使用肥胖药物的敏感性非常低(分别为 10%和 1%);肥胖风险模型确定了另外 22%的肥胖参保者。将百分位切点从第 70 个百分位到第 99 个百分位变化,阳性预测值从 15.5%到 59.2%不等。肥胖风险评分对于检测 BMI≥35kg/m2具有高度特异性,并且大大增加了对肥胖参保者的检测,超过了提供者编码的肥胖诊断或药物索赔。该模型可用于肥胖症护理管理和健康促进,或用于肥胖症相关研究。