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表面污染对周围有环形骨缺损的牙种植体骨整合的影响。

Effect of surface contamination on osseointegration of dental implants surrounded by circumferential bone defects.

机构信息

Dublin Dental School and Hospital, Division of Restorative Dentistry and Periodontology, Dublin, Ireland.

出版信息

Clin Oral Implants Res. 2010 May;21(5):513-9. doi: 10.1111/j.1600-0501.2010.01913.x.

Abstract

OBJECTIVE

This study was designed to evaluate the effect of surface contamination on osseointegration of dental implants surrounded by a circumferential bone defect and to compare osseointegration around Osseotite with that around Nanotite implants.

MATERIALS AND METHODS

The premolars on both sides of the mandible in four beagle dogs were extracted. Following 4 months healing, two Nanotite implants and two Osseotite implants were partially inserted in the left side of each mandible. Some threads protruded from the tissues into the oral cavity. Following a 5 week healing period, the implants were removed and the contaminated part of each implant was cleaned. They were then installed to the full implant length on the contra lateral side of the mandibles. The coronal 5 mm of each implant was surrounded by 1 mm circumferential bone defect. Following 12 weeks of healing period, the dogs were sacrificed and biopsies were obtained. Ground sections were prepared for histomorphometric analysis.

RESULTS

All implants were associated with direct bone-to-implant contact on the portion of the implant surface contaminated previously and surrounded by bone defect. Nanotite implants performed better than Osseotite implants.

CONCLUSIONS

The results demonstrated that implant surfaces, which were contaminated previously and were surrounded by bone defects, can osseointegrate.

摘要

目的

本研究旨在评估表面污染对环绕周缘骨缺损的牙种植体骨整合的影响,并比较 Osseotite 种植体与 Nanotite 种植体周围的骨整合情况。

材料和方法

将 4 只比格犬的下颌双侧前磨牙拔除。愈合 4 个月后,在每只下颌骨的左侧部分植入 2 个 Nanotite 种植体和 2 个 Osseotite 种植体。部分螺纹从组织中突入口腔。愈合 5 周后,取出种植体并清洁每个种植体的污染部分。然后将它们安装到下颌骨对侧的全长。每个种植体的冠部 5mm 周围有 1mm 的周缘骨缺损。愈合 12 周后,处死犬只并获取活检。制备磨片进行组织形态计量学分析。

结果

所有种植体在先前受污染且被骨缺损环绕的种植体表面部分均与直接骨-种植体接触。Nanotite 种植体的表现优于 Osseotite 种植体。

结论

结果表明,先前受污染且被骨缺损环绕的种植体表面可以实现骨整合。

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