Dept. Of Public Policy and Choice University of Eastern Piedmont, Italy.
Sci Total Environ. 2010 Jul 15;408(16):3092-5. doi: 10.1016/j.scitotenv.2010.04.022. Epub 2010 May 4.
Formalin as a fixative has no practical substitutes, but is toxic and potentially carcinogenic, so caution of its use in hospitals and elsewhere is mandatory. In our hospital, preservation of surgical specimens into formalin to be transferred to pathology labs was replaced by under-vacuum sealing (UVS) tissues into plastic bags and preservation at 4 degrees C until transfer. Data analysis showed UVS processing to be superior in terms of staff satisfaction and of gross anatomic preservation; no problems in terms of technical feasibility or histopathologic preservation were encountered. Formalin was confined to pathology labs while its use on hospital premises was vastly reduced.
福尔马林作为一种固定剂没有实际的替代品，但它具有毒性和潜在的致癌性，因此在医院和其他地方使用时必须小心。在我们医院，将手术标本保存在福尔马林中并转移到病理实验室的做法已被真空密封（UVS）组织并保存在塑料袋中，在 4 摄氏度下保存直到转移所取代。数据分析表明，UVS 处理在工作人员满意度和大体解剖保存方面具有优势；在技术可行性或组织病理学保存方面没有遇到问题。福尔马林被限制在病理实验室使用，而在医院内的使用则大大减少。
