[慢性肾衰竭中的钙过敏：3例]
[Calciphylaxis in chronic renal failure: 3 cases].
作者信息
Kaaroud Hayet, Béji Soumaya, Souissi Inés, Ben Hamida Fethi, Zouaghi Karim, Ben Moussa Fatma, El Younsi Fethi, Abderrahim Ezzedine, Ben Abdallah Taieb, Ben Maiz Hédi, Kheder Adel
机构信息
Service de Médecine Interne A, Hôpital Charles Nicolle, Tunis.
出版信息
Tunis Med. 2010 Apr;88(4):261-4.
BACKGROUND
Calciphylaxis is a small vessel disease responsible for vascular calcification and skin necrosis. It occurs in association with chronic renal failure and has a poor prognosis. BUT: Report new cases. We report 3 cases of calciphylaxis occurred in patients with chronic renal failure secondary to interstitial nephritis in 1 case, diabetic nephropathy in 1 case and thrombotic microangiopathy in 1 case.
CASES
They were 2 females an 1 man aged of 44, 3 years meanly. Hyperphosphoremia and hyperparathyroidism were the essential risk factors. All patients died by sepsis. This course was precipitating by corticotherapy in 2 cases.
CONCLUSION
Early recognition and treatment of risk factors is mandatory to reduce mortality in uremic patients with calciphylaxis.
背景
钙过敏是一种导致血管钙化和皮肤坏死的小血管疾病。它与慢性肾衰竭相关，预后较差。但是：报告新病例。我们报告了3例钙过敏病例，其中1例继发于间质性肾炎的慢性肾衰竭患者，1例糖尿病肾病患者，1例血栓性微血管病患者。
病例
他们是2名女性和1名44岁男性，平均年龄3岁。高磷血症和甲状旁腺功能亢进是主要危险因素。所有患者均死于败血症。2例患者的病程因皮质激素治疗而加速。
结论
早期识别和治疗危险因素对于降低尿毒症性钙过敏患者的死亡率至关重要。
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