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食管失弛缓症——测压模式

Esophageal achalasia--manometric patterns.

作者信息

Dumitraşcu D L, Surdea-Blaga Teodora, David Liliana

机构信息

Iuliu Haţieganu University of Medicine and Pharmacy, 2nd Department of Internal Medicine, Cluj-Napoca, Romania.

出版信息

Rom J Intern Med. 2009;47(3):243-7.

Abstract

Achalasia is a primary esophageal motility disorder involving the body of the esophagus and lower esophageal sphincter. Esophageal manometry is the gold standard to diagnose achalasia. Two cardinal features are encountered in achalasia: incomplete LES relaxation and absent peristalsis in the lower esophagus. In a group of 94 patients with dysphagia we looked for the manometric changes, trying to identify clinical and manometric particularities of the cases with achalasia. 35 cases had manometric changes compatible with the diagnostic of achalasia. A number of 41 patients had other esophageal motility disorders and 8 patients had normal esophageal manometry. The majority of patients (80%) had an increase basal pressure in the lower esophageal sphincter (LES) and the rest of them had a normal pressure of the LES. Absence of the lower esophageal sphincter relaxation or incomplete relaxation was observed in all cases. Aperistalsis was found in 33 patients (94.3%) and 2 patients (5.7%) presented hyperperistaltism of the tubular esophagus. We followed the manometric changes pre and post treatment in 10 cases, all having similar manometric modifications, before and after treatment; only the basal pressure of the lower esophageal sphincter was modified after treatment.

摘要

贲门失弛缓症是一种原发性食管动力障碍性疾病,累及食管体部和食管下括约肌。食管测压是诊断贲门失弛缓症的金标准。贲门失弛缓症有两个主要特征:食管下括约肌松弛不完全和食管下段蠕动消失。在一组94例吞咽困难患者中,我们观察其测压变化,试图确定贲门失弛缓症患者的临床和测压特点。35例患者的测压变化符合贲门失弛缓症的诊断。41例患者有其他食管动力障碍,8例患者食管测压正常。大多数患者(80%)食管下括约肌基础压力升高,其余患者食管下括约肌压力正常。所有病例均观察到食管下括约肌松弛缺失或松弛不完全。33例患者(94.3%)出现蠕动消失,2例患者(5.7%)出现食管管状部蠕动亢进。我们对10例患者治疗前后的测压变化进行了随访,所有患者治疗前后的测压改变相似;治疗后仅食管下括约肌基础压力发生改变。

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