Koshikawa Megumi, Ikeda Uichi
Department of Cardiovascular Medicine, Shinshu University.
Nihon Rinsho. 2010 May;68(5):926-9.
The goal of treatment in arteriosclerosis obliterans (ASO) is to aggressively treat atherosclerotic risk factors to reduce future cardiovascular events as well as to improve symptoms of claudication and prevent limb amputation. Patients with ASO have an increased risk of cardiovascular events such as myocardial infarction and stroke in addition to significant impairment in their quality of life and physical function. Strategies for management of ASO include conservative treatment with risk factor modification, smoking cessation, exercise, pharmacologic therapy, balloon angioplasty and stenting of vessels, or bypass surgery, and therapeutic angiogenesis. In addition, the prevention and treatment for cardiovascular events such as myocardial infarction and stroke are important, too.
闭塞性动脉硬化（ASO）的治疗目标是积极治疗动脉粥样硬化危险因素，以减少未来心血管事件的发生，同时改善间歇性跛行症状并预防肢体截肢。除了生活质量和身体功能受到严重损害外，ASO患者发生心血管事件（如心肌梗死和中风）的风险也会增加。ASO的管理策略包括通过改变危险因素进行保守治疗、戒烟、运动、药物治疗、血管球囊血管成形术和支架置入术、旁路手术以及治疗性血管生成。此外，心肌梗死和中风等心血管事件的预防和治疗也很重要。
