Hosaka Y, Togashi K
Division of Thoracic Surgery, Japanese Red Cross Nagaoka Hospital, Nagaoka, Japan.
Kyobu Geka. 2010 May;63(5):383-7.
A 73 year-old woman was diagnosed as thymoma with myasthenia gravis (MG) [ocular type] 18 years ago, but she rejected surgical treatment. The remission of myasthenia gravis has been obtained by treatment of medication. This time, to avoid myasthenic crisis at the time of orthopedic surgery, she underwent surgical treatment for thymoma: extended-thymectomy, resection of the left brachiocephalic vein and reconstraction using ringed polytetrafluoroethylene (ePTFE) graft. Pathologic diagnosis was Masaoka stage III thymoma and World Health Organization (WHO) type B2 + B3. After orthopedic surgery, irradiation was performed for mediastinum. During this period from the resection of thymoma to irradiation, she developed gradually progressive anemia, and as a result of bone marrow examination, she was diagnosed as pure red cell aplasia (PRCA). PRCA has improved with immunosuppressive treatment. One year have passed with no recurrence of thymoma and PRCA.
一名73岁女性18年前被诊断为胸腺瘤合并重症肌无力（MG）[眼肌型]，但她拒绝手术治疗。通过药物治疗，重症肌无力已得到缓解。此次，为避免骨科手术时发生重症肌无力危象，她接受了胸腺瘤手术治疗：扩大胸腺切除术、切除左头臂静脉并使用带环聚四氟乙烯（ePTFE）移植物进行重建。病理诊断为Masaoka III期胸腺瘤，世界卫生组织（WHO）B2 + B3型。骨科手术后，对纵隔进行了放疗。在从胸腺瘤切除到放疗的这段时间里，她逐渐出现进行性贫血，经骨髓检查，被诊断为纯红细胞再生障碍性贫血（PRCA）。PRCA通过免疫抑制治疗已有所改善。现已过去一年，胸腺瘤和PRCA均未复发。
