肥大细胞脱粒肽可使小鼠体温过低。
Mastoparan induces hypothermia in mice.
作者信息
Duvdevani P, Ishay J S, Schejter A
机构信息
Department of Physiology and Pharmacology, Sackler Medical School, Tel Aviv University, Ramat Aviv, Israel.
出版信息
Experientia. 1991 May 15;47(5):460-2. doi: 10.1007/BF01959944.
The polypeptide mastoparan, isolated from the venom of the Oriental Hornet, Vespa orientalis, induces hypothermia in white mice 15 minutes after its intraperitoneal injection. The hypothermic effect is induced by mastoparan obtained from different hornet and wasp venoms. The normal murine core temperature is lowered by mastoparan from 38 degrees C to as far as 33 degrees C. This lowering lasts for one hour and is reversible.
从东方大黄蜂（Vespa orientalis）毒液中分离出的多肽马斯托帕拉宁，在腹腔注射15分钟后可使小白鼠体温降低。从不同黄蜂毒液中获得的马斯托帕拉宁均可产生降温效果。正常小鼠的核心体温可被马斯托帕拉宁从38摄氏度降至33摄氏度。这种体温降低可持续一小时且是可逆的。
Zotero 插件