Hunan Provincial Key Laboratory of Crop Germplasm Innovation and Utilization, College of Agriculture and College of Plant Bio-Safety, Hunan Agricultural University, Changsha, Hunan 410128, China.
Mol Plant Pathol. 2010 May;11(3):419-27. doi: 10.1111/j.1364-3703.2009.00607.x.
Rice blast, caused by the fungal pathogen Magnaporthe oryzae, is the most devastating disease of rice and severely affects crop stability and sustainability worldwide. This disease has advanced to become one of the premier model fungal pathosystems for host-pathogen interactions because of the depth of comprehensive studies in both species using modern genetic, genomic, proteomic and bioinformatic approaches. Many fungal genes involved in pathogenicity and rice genes involved in effector recognition and defence responses have been identified over the past decade. Specifically, the cloning of a total of nine avirulence (Avr) genes in M. oryzae, 13 rice resistance (R) genes and two rice blast quantitative trait loci (QTLs) has provided new insights into the molecular basis of fungal and plant interactions. In this article, we consider the new findings on the structure and function of the recently cloned R and Avr genes, and provide perspectives for future research directions towards a better understanding of the molecular underpinnings of the rice-M. oryzae interaction.
稻瘟病由真菌病原体稻瘟病菌引起，是水稻最具破坏性的病害，严重影响全球作物的稳定性和可持续性。由于在这两个物种中使用现代遗传、基因组、蛋白质组学和生物信息学方法进行了深入的综合研究，该病害已成为主要的真菌病原体模型系统之一。在过去十年中，已经鉴定出许多与致病性有关的真菌基因和与效应子识别和防御反应有关的水稻基因。具体来说，总共克隆了 9 个稻瘟病菌无毒基因（Avr）、13 个水稻抗性基因和 2 个水稻稻瘟病数量性状位点（QTL），为真菌和植物相互作用的分子基础提供了新的见解。在本文中，我们考虑了最近克隆的 R 和 Avr 基因的结构和功能的新发现，并为未来的研究方向提供了展望，以更好地理解水稻-稻瘟病菌相互作用的分子基础。
