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BRCA 携带者对与胚胎植入前遗传学诊断和生育相关的风险管理的看法:当选择过多时,和没有选择一样困难。

BRCA carriers' thoughts on risk management in relation to preimplantation genetic diagnosis and childbearing: when too many choices are just as difficult as none.

机构信息

Health Outcomes and Behavior Program, Division of Population Sciences, Moffitt Cancer Center, Department of Oncologic Science, College of Medicine, University of South Florida, Tampa, Florida 33612, USA.

出版信息

Fertil Steril. 2010 Nov;94(6):2473-5. doi: 10.1016/j.fertnstert.2010.03.064. Epub 2010 May 5.

DOI:10.1016/j.fertnstert.2010.03.064
PMID:20447630
Abstract

Women with a BRCA mutation have unique concerns about childbearing and future fertility. In a focus group conducted among unaffected carriers, the majority of women held positive attitudes toward preimplantation genetic diagnosis to reduce transmission to future offspring and further identified unmet needs for education and support for decision making.

摘要

携带 BRCA 基因突变的女性对生育和未来的生育能力有独特的担忧。在对未受影响的携带者进行的焦点小组中,大多数女性对植入前遗传学诊断持积极态度,以降低向未来后代传播的风险,并且进一步确定了在教育和决策支持方面的未满足需求。

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