Department of Biochemistry and Microbiology, Nelson Mandela Metropolitan University, PO Box 77 000, Port Elizabeth 6031, South Africa.
Ecotoxicol Environ Saf. 2011 Jan;74(1):74-7. doi: 10.1016/j.ecoenv.2010.04.005. Epub 2010 May 5.
Free-living freshwater cyanobacteria contain BMAA in both free cellular and protein-associated forms. Free BMAA released on bloom collapse or during cellular turnover creates a potential source of the non-proteinogenic amino acid for bioaccumulation and biomagnification in aquatic ecosystems. Uptake of free amino acids is well documented in macrophytes and the potential for aquatic macrophytes to bioaccumulate BMAA therefore poses a potential threat where such macrophytes constitute a food source in an ecosystem. BMAA uptake and accumulation by the aquatic macrophyte Ceratophyllum demersum was therefore investigated. Rapid uptake of significant amounts of BMAA was observed in C. demersum. Both free and protein-associated BMAA were observed with protein association following accumulation of free BMAA. The protein association suggests potential biomaccumulation by aquatic macrophytes and offers a possibility of phytoremediation for BMAA removal.
自由生活的淡水蓝藻以游离细胞和与蛋白质结合的两种形式存在 BMAA。在水华崩溃或细胞更替期间释放的游离 BMAA 为非蛋白氨基酸在水生生态系统中的生物积累和生物放大创造了潜在来源。在大型植物中,人们已经很好地记录了游离氨基酸的摄取,因此,当这些大型植物构成生态系统中的食物来源时,水生大型植物具有积累 BMAA 的潜力,这构成了一种潜在威胁。因此,研究了水生大型植物金鱼藻对 BMAA 的摄取和积累。在金鱼藻中观察到大量 BMAA 的快速摄取。游离和与蛋白质结合的 BMAA 都被观察到,在游离 BMAA 积累后出现与蛋白质结合。这种蛋白质结合表明水生大型植物可能具有生物积累能力,并为 BMAA 的去除提供了植物修复的可能性。