胺与 Pd-N-杂环卡宾配合物的合成及结构研究。

Synthetic and structural studies on amine coordination to Pd-N-heterocyclic carbene complexes.

机构信息

Christopher Ingold Laboratories, Department of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ.

出版信息

Dalton Trans. 2009 Sep 21(35):7094-8. doi: 10.1039/b907102d. Epub 2009 Jul 21.

PMID:20449153

Abstract

The reaction between 2-chlorobenzylamine or 2-chlorobenzylalcohol and Pd(I(t)Bu)(2) (I(t)Bu = 1,3-di-tert-butylimidazol-2-ylidene) in benzene affords the dimeric complexes Pd(I(t)Bu)(mu-NH{2-CH(2)C(6)H(4)}) and Pd(I(t)Bu)(mu-O{2-CH(2)C(6)H(4)}); the latter has been structurally characterised. The syntheses, structural characterisation and reactivity of the Pd-NHC amine complexes [(I(t)Bu)Pd(R-4-C(6)H(4))(morpholine)Cl] (R = Me, OMe, CO(2)Me), intermediates in the Buchwald-Hartwig aryl amination reaction, are also reported.

摘要

2-氯苄胺或 2-氯苄醇与 Pd(I(t)Bu)(2)（I(t)Bu = 1,3-二-叔丁基咪唑-2-亚基）在苯中反应生成二聚体配合物Pd(I(t)Bu)(mu-NH{2-CH(2)C(6)H(4)})和Pd(I(t)Bu)(mu-O{2-CH(2)C(6)H(4)})；后者的结构已得到确定。还报道了钯-NHC 胺配合物[(I(t)Bu)Pd(R-4-C(6)H(4))(morpholine)Cl]（R = Me，OMe，CO(2)Me）的合成、结构表征和反应性，它们是 Buchwald-Hartwig 芳基胺化反应的中间体。