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肺移植受者巨细胞病毒再激活后发生的移植后淋巴细胞增生性疾病。

Post-transplant lymphoproliferative disorder following cytomegalovirus reactivation in a lung recipient.

作者信息

Aoyama Akihiro, Omasa Mitsugu, Kondo Nobuyuki, Chen Fengshi, Date Hiroshi, Bando Toru

机构信息

Department of Thoracic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

出版信息

Gen Thorac Cardiovasc Surg. 2010 May;58(5):251-4. doi: 10.1007/s11748-009-0526-x. Epub 2010 May 7.

Abstract

Post-transplant lymphoproliferative disorder (PTLD) is a life-threatening complication after lung transplantation, for which several risk factors including pretransplant seronegativity for Epstein-Barr virus are known. However, the impact of cytomegalovirus on PTLD remains to be determined. Here, we describe a case of Epstein-Barr virus-associated polymorphic PTLD that developed shortly after treatment for cytomegalovirus reactivation in a lung transplant recipient who was preoperatively seropositive for both cytomegalovirus and Epstein-Barr virus.

摘要

移植后淋巴细胞增生性疾病(PTLD)是肺移植后一种危及生命的并发症,已知其有多种危险因素,包括移植前针对Epstein-Barr病毒的血清阴性。然而,巨细胞病毒对PTLD的影响仍有待确定。在此,我们描述了一例与Epstein-Barr病毒相关的多形性PTLD病例,该病例发生在一名肺移植受者巨细胞病毒再激活治疗后不久,该受者术前巨细胞病毒和Epstein-Barr病毒血清均呈阳性。

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