Aoyama Akihiro, Omasa Mitsugu, Kondo Nobuyuki, Chen Fengshi, Date Hiroshi, Bando Toru
Department of Thoracic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Gen Thorac Cardiovasc Surg. 2010 May;58(5):251-4. doi: 10.1007/s11748-009-0526-x. Epub 2010 May 7.
Post-transplant lymphoproliferative disorder (PTLD) is a life-threatening complication after lung transplantation, for which several risk factors including pretransplant seronegativity for Epstein-Barr virus are known. However, the impact of cytomegalovirus on PTLD remains to be determined. Here, we describe a case of Epstein-Barr virus-associated polymorphic PTLD that developed shortly after treatment for cytomegalovirus reactivation in a lung transplant recipient who was preoperatively seropositive for both cytomegalovirus and Epstein-Barr virus.
移植后淋巴细胞增生性疾病(PTLD)是肺移植后一种危及生命的并发症,已知其有多种危险因素,包括移植前针对Epstein-Barr病毒的血清阴性。然而,巨细胞病毒对PTLD的影响仍有待确定。在此,我们描述了一例与Epstein-Barr病毒相关的多形性PTLD病例,该病例发生在一名肺移植受者巨细胞病毒再激活治疗后不久,该受者术前巨细胞病毒和Epstein-Barr病毒血清均呈阳性。