快速眼动睡眠行为障碍。

REM sleep behavior disorder.

机构信息

Department of Neurology, University of Sherbrooke, 3001 12e Avenue Nord, Sherbrooke, QC, J1H 5N4, Canada.

出版信息

Med Clin North Am. 2010 May;94(3):593-614. doi: 10.1016/j.mcna.2010.02.010.

DOI:10.1016/j.mcna.2010.02.010

PMID:20451035

Abstract

REM sleep behavior disorder (RBD), formally recognized in the 1980s, is an infrequent but spectacular parasomnia characterized by dream enactment, leading to aggressive or complex behaviors. It essentially affects older men, and many years may go by before medical attention is sought. Frequent association with the alpha-synucleinopathies,-such as Parkinson disease, has led investigators to believe that idiopathic RBD is not necessarily a benign condition. Diagnosis is confirmed with a polysomnogram, which typically shows absence of normal REM sleep atonia and sometimes abnormal behavior. Treatment is achieved with clonazepam.

摘要

快速眼动睡眠行为障碍（RBD）于 20 世纪 80 年代正式被认识，是一种不常见但很显著的睡眠行为障碍，其特征是梦境演绎，导致攻击性行为或复杂行为。它主要影响老年男性，可能需要多年时间才会寻求医疗关注。经常与 α-突触核蛋白病相关，如帕金森病，这导致研究人员认为特发性 RBD不一定是良性疾病。诊断通过多导睡眠图确认，通常显示正常快速眼动睡眠去抑制缺失，有时还伴有异常行为。治疗方法是使用氯硝西泮。