男性小儿泌尿科疾病所致不育的遗传与表型基础。
The genetic and phenotypic basis of infertility in men with pediatric urologic disorders.
机构信息
Department of Urology, Stanford University School of Medicine, Stanford, CA 94305, USA.
出版信息
Urology. 2010 Jul;76(1):25-31. doi: 10.1016/j.urology.2010.03.011. Epub 2010 May 7.
Male factor is a major component of infertility for many couples. The presence of congenital genitourinary anomalies in male partners can cause male infertility. We reviewed the state-of-the-art treatment and outcomes for male infertility caused by pediatric urologic disorders. Disorders were classified by whether they led to infertility through pre-testis, testicular, or post-testis effects. Despite the complexity of pediatric urologic disorders that can affect fertility, natural paternity and paternity through assisted reproductive technology are common. Given the significant recent advances in infertility treatments, paternity with many currently untreatable pediatric disorders is likely in the future.
男性因素是许多夫妇不孕的主要原因。男性伴侣先天性泌尿生殖系统异常可导致男性不育。我们回顾了儿科泌尿科疾病引起的男性不育的最新治疗方法和结果。这些疾病根据其导致不育的机制分为睾丸前、睾丸和睾丸后因素。尽管儿科泌尿科疾病可能影响生育能力的复杂性，但通过自然生育和辅助生殖技术获得亲权的情况很常见。鉴于目前不孕治疗的重大进展，未来可能会有许多目前无法治疗的儿科疾病也能获得亲权。
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