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应用皮质松质新鲜冷冻骨屑进行上颌窦提升的临床、组织学和组织形态计量学研究。

Clinical, histological and histomorphometrical study of maxillary sinus augmentation using cortico-cancellous fresh frozen bone chips.

机构信息

Department of Maxillo-Facial Surgery, Faculty of Medicine, University of Florence, Florence, Italy.

出版信息

J Craniomaxillofac Surg. 2011 Apr;39(3):192-9. doi: 10.1016/j.jcms.2010.03.019. Epub 2010 May 7.

Abstract

BACKGROUND

Insufficient bone volume in the posterior maxilla can be a major problem when placing dental implants. One of the goals of sinus augmentation procedures is the creation of sufficient volume of vital bone for the subsequent insertion and complete osseointegration of implants placed in the posterior maxilla. The aim of the present study was a clinical, histological and histomorphometrical analysis of maxillary sinus augmentation using human fresh frozen bone (FFB) allografts for maxillary sinus lift augmentation procedures.

METHODS

Fifteen patients were treated with maxillary sinus augmentation using FFB. After three months, a bone biopsy was taken before implant placement in order to evaluate the healed bone from a histological and histomorphometrical point of view. After further three months, all implants were osseointegrated according to radiographic and clinical examinations. Abutment connection was performed and the patients received prosthetic restoration of the missing teeth.

RESULTS

Histologically all the specimens showed signs of active remodelling and all the tissues were free of inflammatory cells. After 12 months of assessment, no implants had failed.

CONCLUSION

Our findings suggest that FFB is a biocompatible material that can be successfully used for maxillary sinus augmentation.

摘要

背景

在上颌后区植入牙种植体时,往往会遇到骨量不足的问题。鼻窦增高术的目标之一是为随后在上颌后区植入的种植体创造足够的有活力的骨量,以实现完全的骨整合。本研究旨在对使用同种异体人冷冻新鲜骨(FFB)进行上颌窦提升术的上颌窦增高进行临床、组织学和组织形态计量学分析。

方法

15 名患者接受了使用 FFB 的上颌窦增高术。在植入前三个月,进行了骨活检,以便从组织学和组织形态计量学的角度评估愈合的骨。进一步三个月后,所有种植体均根据影像学和临床检查实现了骨整合。完成基台连接,为缺失的牙齿进行修复。

结果

组织学上所有标本均显示活跃的重塑迹象,且所有组织均无炎症细胞。在 12 个月的评估后,没有种植体失败。

结论

我们的研究结果表明,FFB 是一种生物相容性材料,可成功用于上颌窦增高。

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