Badellino F, Margarino G, Scala M, Catturich A, Mereu P
Division of Surgical Oncology, Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy.
Int Surg. 1991 Jan-Mar;76(1):49-51.
Surgery is the treatment of choice for thyroid cancer, often followed by I131 and thyroid hormone to control the local residual tumor and distant metastasis. Hundred and sixty-two patients with thyroid disease underwent surgery at the Division of Surgical Oncology of the Cancer Institute in Genoa. Thirty cases presented no malignant hot thyroid nodules, 37 of the other 132 cases were cancers (28%). In 23 cases (62%), the pathological diagnosis was papillary carcinoma, in ten cases (27%) follicular carcinoma, in four (11%) medullary carcinoma. In 13 cases (35%) (ten papillary carcinoma, two follicular carcinoma, one medullary carcinoma) the lesion was multicentric. Our data suggest that total thyroidectomy, performed in two steps, in most cases does not carry important post-operative morbidity but offers the greatest potential for cure. In our cases only one patient died (of the cancer). After radical surgery it is possible to detect and treat metastases by I131.
手术是甲状腺癌的首选治疗方法，术后常辅以碘-131和甲状腺激素来控制局部残留肿瘤及远处转移。162例甲状腺疾病患者在热那亚癌症研究所外科肿瘤学部接受了手术。30例患者无恶性甲状腺热结节，其他132例中有37例为癌症（28%）。23例（62%）病理诊断为乳头状癌，10例（27%）为滤泡状癌，4例（11%）为髓样癌。13例（35%）（10例乳头状癌、2例滤泡状癌、1例髓样癌）病变为多中心性。我们的数据表明，分两步进行的全甲状腺切除术在大多数情况下不会带来严重的术后发病率，但具有最大的治愈潜力。在我们的病例中，只有1例患者死于癌症。根治性手术后，通过碘-131可以检测和治疗转移灶。
