Fegiz G, Ramacciato G, D'Angelo F, Barillari P, Indinnimeo M, Gozzo P, Aurello P, Valabrega S, De Angelis R
Istituto di I Clinica Chirurgica Università degli Studi di Roma La Sapienza.
Int Surg. 1991 Jan-Mar;76(1):58-63.
Personal experience is reported of 47 consecutive liver resections for metastatic colorectal carcinoma treated in the I Clinica Chirurgica of the University of Rome for the purpose of contributing to treatment and evaluating the clinical factors and possible determinants of prognosis that could be potentially predictive of outcome and length of survival after liver resection: Duke's stage of primary colorectal cancer, synchronous or metachronous disease, number of hepatic lesions. Patients were classified according to the proposed staging system of the "Istituto Nazionale Tumori" in Milan. For Stage I and II patients the median survival time was 15 months, while in Stage III patients survival time was reduced to only 4.5 months. The 3- and 5-year survival rate was 20% and 12% respectively for Stage I patients; no patients at stage II or III survived more than 3 years.
本文报告了罗马大学第一外科连续进行的47例转移性结直肠癌肝切除术的个人经验，目的是为治疗提供参考，并评估可能预测肝切除术后预后和生存时间的临床因素及潜在决定因素：原发性结直肠癌的杜克分期、同时性或异时性疾病、肝内病变数量。患者根据米兰“国家肿瘤研究所”提出的分期系统进行分类。I期和II期患者的中位生存时间为15个月，而III期患者的生存时间缩短至仅4.5个月。I期患者的3年和5年生存率分别为20%和12%；II期或III期患者无一人存活超过3年。
