Intensive Care Unit Registrar, Royal Children's Hospital, Melbourne, Australia.
Pediatr Crit Care Med. 2011 Jan;12(1):57-60. doi: 10.1097/PCC.0b013e3181e2a437.
To describe the clinical course of a group of patients who received a rotating inotrope regimen, including levosimendan, for decompensated congestive heart failure.
Case series.
Pediatric intensive care unit in a tertiary care children's hospital.
Nine pediatric patients with severe, decompensated heart failure.
The study patients received a rotating inotrope regimen, including levosimendan, dobutamine, and, in some cases, milrinone.
Six patients were weaned from positive-pressure ventilation. Eight patients were discharged from the intensive care unit, and seven survived to hospital discharge. Two patients were successfully bridged to orthotopic cardiac transplantation. The therapies were generally well tolerated.
Rotating inotropes were safe and seemed to be effective in this heterogeneous population of infants and children with decompensated heart failure. This therapeutic regimen warrants prospective comparative analysis.
描述一组接受旋转正性肌力药物治疗方案（包括左西孟旦）的心力衰竭失代偿患者的临床病程。
病例系列研究。
三级儿童医院儿科重症监护病房。
9 例严重心力衰竭失代偿的儿科患者。
研究患者接受了旋转正性肌力药物治疗方案，包括左西孟旦、多巴酚丁胺，在某些情况下还使用米力农。
6 例患者成功撤离有创正压通气。8 例患者从重症监护病房出院，7 例患者存活至出院。2 例患者成功桥接至原位心脏移植。这些治疗通常耐受良好。
在这组患有心力衰竭失代偿的婴儿和儿童的异质人群中，旋转正性肌力药物是安全且有效的。这种治疗方案需要前瞻性比较分析。
