Suppr超能文献

用于平流-电扩散的浸入边界法,采用隐式时间步长和局部网格细化。

The immersed boundary method for advection-electrodiffusion with implicit timestepping and local mesh refinement.

作者信息

Lee Pilhwa, Griffith Boyce E, Peskin Charles S

机构信息

Department of Cell Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-3505.

出版信息

J Comput Phys. 2010 Jul 1;229(13):5208-5227. doi: 10.1016/j.jcp.2010.03.036.

Abstract

We describe an immersed boundary method for problems of fluid-solute-structure interaction. The numerical scheme employs linearly implicit timestepping, allowing for the stable use of timesteps that are substantially larger than those permitted by an explicit method, and local mesh refinement, making it feasible to resolve the steep gradients associated with the space charge layers as well as the chemical potential, which is used in our formulation to control the permeability of the membrane to the (possibly charged) solute. Low Reynolds number fluid dynamics are described by the time-dependent incompressible Stokes equations, which are solved by a cell-centered approximate projection method. The dynamics of the chemical species are governed by the advection-electrodiffusion equations, and our semi-implicit treatment of these equations results in a linear system which we solve by GMRES preconditioned via a fast adaptive composite-grid (FAC) solver. Numerical examples demonstrate the capabilities of this methodology, as well as its convergence properties.

摘要

我们描述了一种用于流体-溶质-结构相互作用问题的浸入边界方法。该数值方案采用线性隐式时间步长,允许稳定使用比显式方法允许的时间步长得多的时间步长,以及局部网格细化,从而能够解析与空间电荷层以及化学势相关的陡峭梯度,我们在公式中使用化学势来控制膜对(可能带电的)溶质的渗透率。低雷诺数流体动力学由与时间相关的不可压缩斯托克斯方程描述,该方程通过单元中心近似投影方法求解。化学物质的动力学由平流-电扩散方程控制,我们对这些方程的半隐式处理导致一个线性系统,我们通过由快速自适应复合网格(FAC)求解器预处理的GMRES来求解该线性系统。数值示例展示了该方法的能力及其收敛特性。

相似文献

9
A Kernel-free Boundary Integral Method for Elliptic Boundary Value Problems.一种用于椭圆型边值问题的无核边界积分方法。
J Comput Phys. 2007 Dec 10;227(2):1046-1074. doi: 10.1016/j.jcp.2007.08.021. Epub 2007 Sep 5.

引用本文的文献

2
Electrophysiology.电生理学
Commun Pure Appl Math. 2013 Dec;66(12):1837-1913. doi: 10.1002/cpa.21484. Epub 2013 Oct 9.
8
Heterogeneous mechanics of the mouse pulmonary arterial network.小鼠肺动脉网络的异质性力学
Biomech Model Mechanobiol. 2016 Oct;15(5):1245-61. doi: 10.1007/s10237-015-0757-y. Epub 2016 Jan 20.

本文引用的文献

2
Growth of dendritic spines: a continuing story.树突棘的生长:一个持续的故事。
Curr Opin Neurobiol. 2005 Feb;15(1):67-72. doi: 10.1016/j.conb.2005.01.015.
3
Calcium dynamics in dendritic spines and spine motility.树突棘中的钙动力学与棘运动性
Biophys J. 2004 Jul;87(1):81-91. doi: 10.1529/biophysj.103.035972.
5
How nematode sperm crawl.线虫精子如何爬行。
J Cell Sci. 2002 Jan 15;115(Pt 2):367-84. doi: 10.1242/jcs.115.2.367.
6
Cardiac excitation-contraction coupling.心脏兴奋-收缩偶联
Nature. 2002 Jan 10;415(6868):198-205. doi: 10.1038/415198a.
7
Water and the cytoskeleton.水与细胞骨架
Cell Mol Biol (Noisy-le-grand). 2001 Jul;47(5):901-23.
9
Neuronal calcium signaling.神经元钙信号传导
Neuron. 1998 Jul;21(1):13-26. doi: 10.1016/s0896-6273(00)80510-3.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验