Lee Pilhwa, Griffith Boyce E, Peskin Charles S
Department of Cell Biology, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030-3505.
J Comput Phys. 2010 Jul 1;229(13):5208-5227. doi: 10.1016/j.jcp.2010.03.036.
We describe an immersed boundary method for problems of fluid-solute-structure interaction. The numerical scheme employs linearly implicit timestepping, allowing for the stable use of timesteps that are substantially larger than those permitted by an explicit method, and local mesh refinement, making it feasible to resolve the steep gradients associated with the space charge layers as well as the chemical potential, which is used in our formulation to control the permeability of the membrane to the (possibly charged) solute. Low Reynolds number fluid dynamics are described by the time-dependent incompressible Stokes equations, which are solved by a cell-centered approximate projection method. The dynamics of the chemical species are governed by the advection-electrodiffusion equations, and our semi-implicit treatment of these equations results in a linear system which we solve by GMRES preconditioned via a fast adaptive composite-grid (FAC) solver. Numerical examples demonstrate the capabilities of this methodology, as well as its convergence properties.
我们描述了一种用于流体-溶质-结构相互作用问题的浸入边界方法。该数值方案采用线性隐式时间步长,允许稳定使用比显式方法允许的时间步长得多的时间步长,以及局部网格细化,从而能够解析与空间电荷层以及化学势相关的陡峭梯度,我们在公式中使用化学势来控制膜对(可能带电的)溶质的渗透率。低雷诺数流体动力学由与时间相关的不可压缩斯托克斯方程描述,该方程通过单元中心近似投影方法求解。化学物质的动力学由平流-电扩散方程控制,我们对这些方程的半隐式处理导致一个线性系统,我们通过由快速自适应复合网格(FAC)求解器预处理的GMRES来求解该线性系统。数值示例展示了该方法的能力及其收敛特性。