Department of Radiology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.
Eur Radiol. 2010 Oct;20(10):2307-14. doi: 10.1007/s00330-010-1807-6. Epub 2010 May 9.
To evaluate if the screening performance parameters of digital mammography (DM) in a decentralized screening organization were comparable with film-screen mammography (FSM).
A nationwide screening program was launched in 2001, and since 2005 screening with DM has been allowed. Firstly, the parameters of the three regional screening units (RSUs) that first switched to DM (11,355 women) were compared with the FSM period of the same three RSUs (23,325 women). Secondly, they were compared with the results of the whole central breast unit (CBU).
The recall rate (RR) of the DM group in the initial round was 2.64% [2.40% for FSM (p = 0.43)] and in the subsequent round 1.20% [1.58% for FSM (p = 0.03)]. The cancer detection rate (CDR) was 0.59% for DM and 0.64% for FSM (p = 0.56). The percentage of ductal carcinoma in situ was 0.07% for DM and 0.16% for FSM (p = 0.02). The positive predictive value was high in the subsequent rounds (DM 48.00%, FSM 45.93%) and lower in the initial round (DM 24.05%, FSM 24.86%). Compared with the results of the whole CBU, DM showed no significant difference.
DM can be introduced in a decentralized screening organization with a high CDR without increasing the RR.
评估在分散式筛查组织中数字乳腺 X 线摄影（DM）的筛查性能参数是否与胶片乳腺 X 线摄影（FSM）相当。
2001 年启动了一项全国性的筛查计划，自 2005 年以来允许进行 DM 筛查。首先，比较了三个最先切换到 DM 的区域筛查单位（RSU）（11355 名女性）的参数与这三个 RSU 的 FSM 时期（23325 名女性）。其次，将其与整个中央乳房单位（CBU）的结果进行比较。
DM 组首轮的召回率（RR）为 2.64%[FSM 为 2.40%（p=0.43）]，后续轮次为 1.20%[FSM 为 1.58%（p=0.03）]。DM 的癌症检出率（CDR）为 0.59%，FSM 为 0.64%（p=0.56）。DM 的导管原位癌（DCIS）百分比为 0.07%，FSM 为 0.16%（p=0.02）。后续轮次的阳性预测值较高（DM 为 48.00%，FSM 为 45.93%），首轮较低（DM 为 24.05%，FSM 为 24.86%）。与整个 CBU 的结果相比，DM 无显著差异。
在高 CDR 情况下，DM 可在分散式筛查组织中引入，而不会增加 RR。
