Reproductive Sciences Branch, Center for Population Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, NIH, DHHS, MD 20892-7510, USA.
Am J Reprod Immunol. 2010 Jun;63(6):413-24. doi: 10.1111/j.1600-0897.2010.00853.x. Epub 2010 Apr 30.
Blastocyst implantation is a process of interaction between embryo and the uterus. To understand this process, this review tries to summarize what blastocyst implantation essential factors (BIEFs) play what roles, as well as where in the uterus and at what stage of implantation process. Addition of more new data to this kind of compilation of information will help the development of diagnosis and treatment of infertility caused by implantation failure. The major, important cells of the endometrial cells that interact with invading blastocyst (trophoblast) are luminal epithelial cells, stromal cells (decidual cells) and resident immune cells. BIEFs regulate these cells to successfully maintain pregnancy.
囊胚着床是胚胎与子宫相互作用的过程。为了理解这个过程，本篇综述试图总结囊胚着床必需因子（BIEFs）在何处、在着床过程的哪个阶段发挥什么作用。向这种信息汇集中添加更多新数据将有助于开发因着床失败导致不孕的诊断和治疗方法。与入侵囊胚（滋养层）相互作用的主要的、重要的子宫内膜细胞是腔上皮细胞、基质细胞（蜕膜细胞）和固有免疫细胞。BIEFs 调节这些细胞以成功维持妊娠。
