Department of Veterinary Science, Small Animal Teaching Hospital, University of Liverpool, Leahurst, Chester High Road, Neston CH64 7TE, UK.
Vet J. 2011 Apr;188(1):39-43. doi: 10.1016/j.tvjl.2010.03.024. Epub 2010 Apr 24.
Sixteen dogs with acute-onset, non-progressive signs of brain dysfunction and magnetic resonance imaging (MRI) characteristics compatible with thalamic infarction are described. Topographically the MRI lesions could be grouped in three thalamic regions, namely, paramedian (8/16), extensive dorsal (5/16) and ventrolateral (3/16). Paramedian lesions resulted in signs typical of vestibular dysfunction. Extensive dorsal lesions were associated with vestibular ataxia, circling and contralateral menace response deficits. Ventrolateral lesions resulted in circling and contralateral proprioceptive deficits. In several dogs, regions other than the thalamus were also affected: four extended into the midbrain; six extended to the internal capsule, and two dogs had a second lesion in the cerebellum. Three clinical syndromes were identified in association with thalamic infarction. These signs varied somewhat, most likely because lesions were not confined to specific nuclear boundaries and involved different combinations of thalamic nuclei.
描述了 16 只出现急性发作、非进行性脑功能障碍症状和符合丘脑梗死的磁共振成像（MRI）特征的犬。根据 MRI 病变的部位，可以将其分为三个丘脑区域，即旁正中（8/16）、广泛背侧（5/16）和腹外侧（3/16）。旁正中病变导致典型的前庭功能障碍症状。广泛背侧病变与前庭共济失调、转圈和对侧威胁反应缺陷有关。腹外侧病变导致转圈和对侧本体感觉缺陷。在一些犬中，除了丘脑之外的其他区域也受到了影响：4 只延伸到中脑；6 只延伸到内囊，有两只犬在小脑有第二个病变。与丘脑梗死相关的有三种临床综合征。这些症状有所不同，最可能的原因是病变不仅局限于特定的核边界，还涉及不同的丘脑核组合。
