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儿童幼年特发性关节炎的营养状况和临床特征。

Nutritional status and clinical characteristics in children with juvenile rheumatoid arthritis.

机构信息

Department of Pediatrics, Far Eastern Memorial Hospital, Taipei, Taiwan.

出版信息

J Microbiol Immunol Infect. 2010 Apr;43(2):93-8. doi: 10.1016/S1684-1182(10)60015-1.

Abstract

BACKGROUND/PURPOSE: The aim of the study was to investigate the clinical characteristics and nutritional status of juvenile rheumatoid arthritis (JRA) in Taiwanese children.

METHODS

Fifty-three patients were included in this study. The disease subtype and patient characteristics were recorded. Body mass index (BMI) was determined. Seventy-five healthy age-matched children served as a control group.

RESULTS

The inflammation parameters, including white blood cell count, platelet count, C-reactive protein, and erythrocyte sedimentation rate, were elevated in the systemic group. The BMI level of the JRA group was significantly lower than the control group (p = 0.006), especially in the male patients (p = 0.016) and when the patient age was greater than 4 (p = 0.011). The patients with oligoarticular onset JRA had significantly lower BMI compared with the healthy control group (p = 0.012).

CONCLUSION

Nutritional status is often impaired in patients with JRA. The BMI of the JRA patients was lower than that of age-matched healthy children, especially in the male group, and when disease onset age was greater than 4. In our unselected sample, the most affected disease subtype was oligoarticular onset JRA.

摘要

背景/目的:本研究旨在探讨台湾儿童幼年特发性关节炎(JRA)的临床特征和营养状况。

方法

本研究纳入了 53 名患者。记录了疾病亚型和患者特征。测定了体重指数(BMI)。75 名年龄匹配的健康儿童作为对照组。

结果

全身型 JRA 的炎症参数(包括白细胞计数、血小板计数、C 反应蛋白和红细胞沉降率)升高。JRA 组的 BMI 水平明显低于对照组(p=0.006),尤其是男性患者(p=0.016)和年龄大于 4 岁的患者(p=0.011)。少关节型 JRA 患者的 BMI 明显低于健康对照组(p=0.012)。

结论

JRA 患者的营养状况常常受损。JRA 患者的 BMI 低于年龄匹配的健康儿童,尤其是男性组和发病年龄大于 4 岁的患者。在我们未选择的样本中,受影响最严重的疾病亚型是少关节型 JRA。

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