Kalager T, Bøe E, Digranes A, Høisaether P, Solberg C O
Infection. 1978;6(1):21-2. doi: 10.1007/BF01641086.
Twenty-eight patients with chronic urinary tract infections were treated with 400 mg pivmecillinam orally three times daily for 10 to 15 days. The diagnosis was confirmed by a history of cystitis or cystopyelitis four to six times annually, microscopy of urine sediment, and growth of pathogens in urine specimens obtained by suprapubic bladder puncture. Three days, three and six weeks after completion of therapy the success rates were 24/28, 20/28 and 19/28 respectively. Pivmecillinam was well tolerated. Two patients developed nausea and vomiting. Other side-effects were not observed. Pivmecillinam is a useful drug in the treatment of chronic urinary tract infections.
28例慢性尿路感染患者接受了口服匹美西林400mg、每日3次、共10至15天的治疗。诊断依据为每年有4至6次膀胱炎或膀胱肾盂炎病史、尿沉渣显微镜检查以及经耻骨上膀胱穿刺获取的尿液标本中病原体生长情况得以确诊。治疗结束后3天、3周和6周时的成功率分别为24/28、20/28和19/28。匹美西林耐受性良好。2例患者出现恶心和呕吐。未观察到其他副作用。匹美西林是治疗慢性尿路感染的一种有效药物。
