与利福布丁治疗克罗恩病相关的持续性角膜内皮沉积物。
Persistent corneal endothelial deposits associated with rifabutin therapy for Crohn's disease.
机构信息
West Kent Eye Centre, Princess Royal University Hospital, South London NHS Trust, Orpington, Kent, United Kingdom.
出版信息
Cornea. 2010 Jun;29(6):706-7. doi: 10.1097/ICO.0b013e3181bd4979.
PURPOSE
To report a case of corneal endothelial deposits associated with rifabutin therapy for Crohn's disease.
METHOD
Case report, anterior segment photography, and current literature search.
RESULTS
Persistence of corneal endothelial deposits was found to occur in a 55-year-old gentleman 6 years after cessation of a 3-year course of rifabutin. The corneal deposits were not associated with lenticular findings or retinal dysfunction, the latter side effect being published in a recent research article.
CONCLUSIONS
This is only the second published case of corneal deposits in conjunction with rifabutin therapy for Crohn's disease. This case uniquely confirms the persistence of the corneal deposits longer than previously documented.
目的
报告一例与利福布丁治疗克罗恩病相关的角膜内皮沉积物病例。
方法
病例报告、眼前段摄影及当前文献检索。
结果
55 岁男性在停止利福布丁治疗 3 年后，发现角膜内皮沉积物持续存在。角膜沉积物与晶状体发现或视网膜功能障碍无关，后者的副作用在最近的一篇研究文章中发表。
结论
这是第二例与利福布丁治疗克罗恩病相关的角膜沉积物的发表病例。该病例独特地证实了角膜沉积物的持续时间长于以前的记录。
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