异硫脲介导的硅基烯酮缩醛的立体选择性 C-酰化反应。
Isothiourea-mediated stereoselective C-acylation of silyl ketene acetals.
机构信息
EaStCHEM, School of Chemistry, University of St Andrews, North Haugh, St. Andrews KY16 9ST, UK.
出版信息
Org Lett. 2010 Jun 4;12(11):2660-3. doi: 10.1021/ol1008747.
PMID:20459078
Abstract
Isothiourea DHPB promotes the diastereoselective C-acylation of silyl ketene acetals with anhydrides or benzoyl fluoride, giving 3-acyl-3-aryl or 3-acyl-3-alkylfuranones in excellent yields and stereoselectivities (up to 99:1 dr).
摘要
异硫脲二氢吡咯并苯并磷促进硅基烯酮缩醛与酸酐或苯甲酰氟的非对映选择性 C-酰化反应，以优异的收率和立体选择性（高达 99:1 dr）得到 3-酰基-3-芳基或 3-酰基-3-烷基呋喃酮。
Zotero 插件