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沙特阿拉伯人群中饮水氟暴露与龋齿、氟斑牙的相关性研究。

Associations among dental caries experience, fluorosis, and fluoride exposure from drinking water sources in Saudi Arabia.

机构信息

Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.

出版信息

J Public Health Dent. 2010 Summer;70(3):220-6. doi: 10.1111/j.1752-7325.2010.00169.x.

Abstract

OBJECTIVES

a) To correlate fluoride levels in drinking water sources with caries experience and dental fluorosis in Saudi Arabia, and suggest appropriate fluoride concentration for drinking water in the country.

METHODS

Fluoride levels were determined from 3,629 samples obtained from drinking water sources in 11 regions of Saudi Arabia. Based on the fluoride concentrations, a stratified sample of subjects aged 6-7, 12-13, and 15-18 years was obtained from the regions. A total of 12,200 selected subjects were examined for dental caries according to the World Health Organization criteria, and dental fluorosis, using Thylstrup and Fejerskov classification.

RESULTS

There was an inverse relationship between fluoride exposure and caries experience, but the prevalence of dental fluorosis increased with increase in fluoride concentration. There was no significant difference in caries experience or in the prevalence of dental fluorosis when fluoride levels increased from 0.3 ppm to 0.6 ppm. In contrast, caries experience was lower, while severity of fluorosis was significantly higher at fluoride levels above 0.6 ppm.

CONCLUSIONS

a) Fluoride levels in drinking water sources in Saudi Arabia correlate significantly with caries experience and prevalence of dental fluorosis. b) Appropriate fluoride concentration for drinking water in Saudi Arabia may be about 0.6 ppm.

摘要

目的

a) 分析沙特阿拉伯饮用水源中的氟化物水平与龋齿患病情况和氟牙症之间的关系,并为该国饮用水推荐适宜的氟化物浓度。

方法

从沙特阿拉伯 11 个地区的饮用水源中采集了 3629 个样本,以确定氟化物水平。根据氟化物浓度,从各地区抽取了 6-7 岁、12-13 岁和 15-18 岁的分层样本。根据世界卫生组织的标准,对 12200 名选定的受试者进行了龋齿检查,并采用 Thylstrup 和 Fejerskov 分类法对氟牙症进行了检查。

结果

氟化物暴露与龋齿患病情况呈负相关,但氟牙症的患病率随着氟化物浓度的增加而增加。当氟化物水平从 0.3ppm 增加到 0.6ppm 时,龋齿患病情况或氟牙症的患病率没有显著差异。相比之下,氟化物水平高于 0.6ppm 时,龋齿患病情况较低,但氟中毒的严重程度显著更高。

结论

a) 沙特阿拉伯饮用水源中的氟化物水平与龋齿患病情况和氟牙症的患病率显著相关。b) 沙特阿拉伯饮用水的适宜氟化物浓度可能约为 0.6ppm。

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