Takigami Iori, Ohara Akira, Matsumoto Kazu, Fukuta Masashi, Shimizu Katsuji
Department of Orthopaedic Surgery, Gifu University Graduate School of Medicine, Gifu, Japan.
J Orthop Surg Res. 2010 May 12;5:33. doi: 10.1186/1749-799X-5-33.
Paget's disease of the bone is a common metabolic bone disease in most European countries, Australia, New Zealand, and North America. Conversely, this disease is rare in Scandinavia, Asia, and Africa. In Japan, it is extremely rare, with a prevalence of 0.15/100000. Paget's disease is a localized disorder of bone remodeling. Excessive bone resorption and abnormal bone formation result in biomechanically weakened bone and predispose patients to fracture. Delayed union and non-union of fractures have been reported in patients with Paget's disease. Therefore, open reduction and internal fixation of fractures has been recommended to prevent such complications. Here we report an unusual case of a 63-year-old Asian woman with delayed union of a femur fracture secondary to Paget's disease, which was treated successfully by functional bracing.
骨佩吉特病在大多数欧洲国家、澳大利亚、新西兰和北美是一种常见的代谢性骨病。相反，这种疾病在斯堪的纳维亚半岛、亚洲和非洲很少见。在日本，它极为罕见，患病率为0.15/100000。佩吉特病是一种局部性的骨重塑紊乱疾病。过度的骨质吸收和异常的骨形成导致骨生物力学强度减弱，使患者易发生骨折。有报道称佩吉特病患者骨折愈合延迟和不愈合。因此，建议对骨折进行切开复位内固定以预防此类并发症。在此，我们报告一例罕见病例，一名63岁的亚洲女性因佩吉特病导致股骨骨折愈合延迟，通过功能性支具治疗成功。
