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肌萎缩侧索硬化症中肌束颤动的检测:所需的观察时间。

Detecting fasciculations in amyotrophic lateral sclerosis: duration of observation required.

机构信息

Department of Clinical Neurssophysiology, King's College Hospital, London SE5 9RS, UK.

出版信息

J Neurol Neurosurg Psychiatry. 2011 May;82(5):549-51. doi: 10.1136/jnnp.2009.186833. Epub 2010 May 12.

DOI:10.1136/jnnp.2009.186833
PMID:20462913
Abstract

A practical issue in the diagnosis of amyotrophic lateral sclerosis (ALS) is how long the EMG must be observed before a muscle can be declared free of fasciculations with some degree of certainty. To answer this question, the intervals between fasciculation potentials (FPs) were recorded from 53 muscles of 19 ALS patients. The distribution of the FP intervals found across the sample showed that to record a single fasciculation with a probability approaching unity, observation for up to 90 s may be required.

摘要

肌萎缩侧索硬化症(ALS)诊断中的一个实际问题是,在多大程度上可以确定肌肉没有肌束震颤,需要观察多长时间的肌电图。为了回答这个问题,记录了 19 名 ALS 患者的 53 块肌肉的肌束震颤电位(FP)的间隔。在整个样本中发现的 FP 间隔分布表明,为了以接近 100%的概率记录单个肌束震颤,可能需要观察长达 90 s。

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