Lychakov D V, Pashchinin A N
Kosm Biol Aviakosm Med. 1991 Jan-Feb;25(1):23-8.
Wistar rats were for 2 weeks exposed to vibrations of 18 Hz (acceleration of 2.3 G applied for 5.8 hrs a day for as long as 58 hrs) and 30 Hz (acceleration of 9.6 G applied for 5.1 hrs a day for as long as 56 hrs). The weight gain of experimental animals was less than that of control rats. Static endurance measured in terms of the time, during which the rats stayed on the vertical pole, decreased in the controls as their weight grew. Static endurance of the experimental rats remained essentially unchanged in spite of their growth. This may be associated with the stimulating effect of vibration on the muscle tone. The turning reflex was investigated using a specially designed unit, which allowed stroboscopic photography that was synchronized with the moment, when the animal began to fall down. The angles between the head and torso as related to the horizontal line were calculated and found to be unaltered in both experimental and control animals during 2 weeks. However, after exposure to vibration of both magnitudes the rats began to position the body off the horizontal line. Morphological examinations revealed no distinct structural changes in the utriculus, sacculus or posterior ampulla of the experimental rats when compared with the controls. At the same time it was demonstrated that the exposure produced swelling of cupulate nerve endings in the central compartment of the receptor epithelium of the posterior ampulla. The time course of morphofunctional changes of the vestibular apparatus in response to vibration of different frequencies (from 6 to 50 Hz) was also examined.
将Wistar大鼠暴露于18 Hz的振动（加速度为2.3 G，每天施加5.8小时，持续58小时）和30 Hz的振动（加速度为9.6 G，每天施加5.1小时，持续56小时）下两周。实验动物的体重增加低于对照大鼠。以大鼠在垂直杆上停留的时间来衡量的静态耐力，在对照大鼠中随着体重增加而下降。尽管实验大鼠体重增加，但其静态耐力基本保持不变。这可能与振动对肌张力的刺激作用有关。使用专门设计的装置研究翻转反射，该装置允许进行与动物开始倒下时刻同步的频闪摄影。计算头部与躯干与水平线之间的角度，发现实验动物和对照动物在两周内该角度均未改变。然而，在暴露于两种强度的振动后，大鼠开始使身体偏离水平线。形态学检查显示，与对照相比，实验大鼠的椭圆囊、球囊或后半规管没有明显的结构变化。同时还表明，暴露导致后半规管感受器上皮中央区的杯状神经末梢肿胀。还研究了前庭器官对不同频率（6至50 Hz）振动的形态功能变化的时间进程。
