• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

胰岛素对睾丸间质细胞促黄体生成素受体的调节作用。

Insulin regulation of Leydig cell luteinizing hormone receptors.

作者信息

Charreau E H, Calvo J C, Tesone M, de Souza Valle L B, Barañao J L

出版信息

J Biol Chem. 1978 Apr 25;253(8):2504-6.

PMID:204651
Abstract

The effect of experimentally induced diabetes on the luteinizing hormone-human chorionic gonadotropin receptors in rat testes was examined. Pancreatectomy and streptozotocin diabetes the gonadotropin receptors and the administration of insulin restored the binding capacity to normal values. No differences in the association constant as well as the sedimentation coefficients of the luteinizing hormone-human chorionic gonadotropin receptor complexes were observed between normal and diabetic animals.

摘要

研究了实验性诱导糖尿病对大鼠睾丸中促黄体生成素-人绒毛膜促性腺激素受体的影响。胰腺切除术和链脲佐菌素诱导的糖尿病会影响促性腺激素受体,而胰岛素治疗可使结合能力恢复到正常水平。在正常动物和糖尿病动物之间,未观察到促黄体生成素-人绒毛膜促性腺激素受体复合物的结合常数以及沉降系数有差异。

相似文献

1
Insulin regulation of Leydig cell luteinizing hormone receptors.胰岛素对睾丸间质细胞促黄体生成素受体的调节作用。
J Biol Chem. 1978 Apr 25;253(8):2504-6.
2
Regulation of gonadotropin receptors and steroidogenesis in cultured porcine Leydig cells.
Endocrinology. 1982 Mar;110(3):933-40. doi: 10.1210/endo-110-3-933.
3
Androgen biosynthesis in Leydig cells after testicular desensitization by luteinizing hormone-releasing hormone and human chorionic gonadotropin.
Endocrinology. 1979 Dec;105(6):1314-21. doi: 10.1210/endo-105-6-1314.
4
Regulation of luteinizing hormone receptors and steroidogenesis in gonadotropin-desensitized leydig cells.
J Biol Chem. 1978 Jun 25;253(12):4297-304.
5
Regulation of luteinizing-hormone-receptors and steroidogenesis in the neonatal rat testis.新生大鼠睾丸中促黄体生成素受体的调控与类固醇生成
Endocrinology. 1981 Aug;109(2):588-95. doi: 10.1210/endo-109-2-588.
6
[Desensitization by human chorionic gonadotropin (hCG): demonstration of a negative control of gonadotropin receptors by hCG at the level of testicular Leydig cells].[人绒毛膜促性腺激素(hCG)脱敏:hCG在睾丸间质细胞水平对促性腺激素受体的负调控作用的证明]
C R Acad Hebd Seances Acad Sci D. 1977 Apr 18;284(15):1429-32.
7
Gonadotropin-induced receptor regulation and steroidogenic lesions in cultured Leydig cells. Induction of specific protein synthesis by chorionic gonadotropin and estradiol.
J Biol Chem. 1981 Dec 25;256(24):12875-82.
8
Differential effects of single and repeated administrations of gonadotropins on luteinizing hormone receptors and testosterone synthesis in two populations of Leydig cells.
J Biol Chem. 1980 Aug 10;255(15):7118-22.
9
Luteinizing hormone receptors and testosterone synthesis in two distinct populations of Leydig cells.
Endocrinology. 1980 May;106(5):1424-9. doi: 10.1210/endo-106-5-1424.
10
A water-soluble human chorionic gonadotropin-binding component obtained from Leydig cell membrane fractions.
Endocrinology. 1978 Mar;102(3):814-23. doi: 10.1210/endo-102-3-814.

引用本文的文献

1
Signatures of metabolic diseases on spermatogenesis and testicular metabolism.代谢性疾病对精子发生和睾丸代谢的影响特征。
Nat Rev Urol. 2024 Aug;21(8):477-494. doi: 10.1038/s41585-024-00866-y. Epub 2024 Mar 25.
2
State of hypophyseogonadal system in male rats with diabetes (experimental investigation).
Neurosci Behav Physiol. 1994 Mar-Apr;24(2):159-62. doi: 10.1007/BF02355673.
3
Androgen receptors in the diabetic rat.糖尿病大鼠中的雄激素受体。
Diabetologia. 1980 May;18(5):385-90. doi: 10.1007/BF00276819.
4
Evaluation of steroid biosynthetic lesions in isolated Leydig cells from the testes of streptozotocin-diabetic rats.
Diabetologia. 1982 Dec;23(6):529-33. doi: 10.1007/BF00254305.
5
Distribution of insulin binding sites on Leydig cells of rat testes using insulin-coated gold particles.使用胰岛素包被的金颗粒研究大鼠睾丸间质细胞上胰岛素结合位点的分布。
Histochemistry. 1992;97(3):213-20. doi: 10.1007/BF00267630.