Charreau E H, Calvo J C, Tesone M, de Souza Valle L B, Barañao J L
J Biol Chem. 1978 Apr 25;253(8):2504-6.
The effect of experimentally induced diabetes on the luteinizing hormone-human chorionic gonadotropin receptors in rat testes was examined. Pancreatectomy and streptozotocin diabetes the gonadotropin receptors and the administration of insulin restored the binding capacity to normal values. No differences in the association constant as well as the sedimentation coefficients of the luteinizing hormone-human chorionic gonadotropin receptor complexes were observed between normal and diabetic animals.
研究了实验性诱导糖尿病对大鼠睾丸中促黄体生成素-人绒毛膜促性腺激素受体的影响。胰腺切除术和链脲佐菌素诱导的糖尿病会影响促性腺激素受体,而胰岛素治疗可使结合能力恢复到正常水平。在正常动物和糖尿病动物之间,未观察到促黄体生成素-人绒毛膜促性腺激素受体复合物的结合常数以及沉降系数有差异。