Johnson Reuben D, Qadri Syed R, Joint C, Moir L, Green A L, Aziz T Z
Nuffield Department of Surgery, University of Oxford and Oxford Functional Neurosurgery, John Radcliffe Hospital, Headley Way, Headington, Oxford, UK.
Br J Neurosurg. 2010 Jun;24(3):289-90. doi: 10.3109/02688690903577631.
Following a total of 386 deep brain stimulation (DBS) procedures in Oxford, only two seizures have been recorded in the peri-operative period. Both patients had MS and underwent thalamic DBS for tremor and these 2 cases are presented here. The incidence of peri-operative seizures in MS patients undergoing DBS procedures is more than 8-fold greater than that expected for patients undergoing DBS procedures. Further experience with DBS procedures in MS patients is needed to determine whether there is a role for peri-operative anticonvulsants in these patients.
在牛津进行的总共386例脑深部电刺激（DBS）手术中，围手术期仅记录到两例癫痫发作。两名患者均患有多发性硬化症（MS），并因震颤接受了丘脑DBS手术，现将这2例病例呈现于此。接受DBS手术的MS患者围手术期癫痫发作的发生率比接受DBS手术的患者预期发生率高出8倍多。需要对MS患者进行DBS手术的更多经验，以确定围手术期抗惊厥药物在这些患者中是否有用。
