Scheltens P, Verhey F R, de Boer M, Wolters E C
Academisch Ziekenhuis Vrije Universiteit, afd. Neurologie, Amsterdam.
Ned Tijdschr Geneeskd. 1991 May 18;135(20):898-901.
Slowly progressive aphasia without dementia is a rare disease, first described in 1982. Since then the existence of a nosological entity bearing that name is disputed. Case histories of two patients are described, with emphasis on clinical presentation and the importance of early diagnosis and neuropsychological evaluation. It is concluded that slowly progressive aphasia is a sign caused by a neurodegenerative cerebral disorder starting in the dominant hemisphere, ultimately accompanied by symptoms of generalised dementia.
无痴呆的缓慢进行性失语是一种罕见疾病，于1982年首次被描述。自那时起，以此命名的疾病实体的存在一直存在争议。本文描述了两名患者的病例史，重点关注临床表现以及早期诊断和神经心理学评估的重要性。得出的结论是，缓慢进行性失语是一种由优势半球起始的神经退行性脑疾病引起的体征，最终会伴有全身性痴呆症状。
