Keane J R
Department of Neurology, Los Angeles County/University of Southern California Medical Center.
Neurology. 1991 Jun;41(6):841-5. doi: 10.1212/wnl.41.6.841.
In 50 hospitalized patients with acquired immunodeficiency syndrome, signs of central eye movement limitation (28 cases) were most common. Peripheral eye movement limitations (18), abnormalities of vision (18), and abnormal spontaneous eye movements (15) occurred with about equal frequency. Meningitis (17), usually due to lymphoma (8) or Cryptococcus (8), was the usual cause of peripheral nervous system involvement, while toxoplasmosis (18) was more common than lymphoma (4) or presumed viral causes (8) in producing CNS dysfunction. The midbrain and pretectal (8) were affected about as often as the pontine tegmentum (9), but rostral brainstem lesions appeared to be the result of toxoplasmosis (4) or lymphoma (3), whereas a viral etiology was the presumed cause of most caudal stem involvement.
在50例住院的获得性免疫缺陷综合征患者中，中枢性眼球运动受限体征（28例）最为常见。外周性眼球运动受限（18例）、视力异常（18例）和异常自发性眼球运动（15例）出现的频率大致相同。脑膜炎（17例）通常由淋巴瘤（8例）或隐球菌（8例）引起，是外周神经系统受累的常见原因，而弓形虫病（18例）在导致中枢神经系统功能障碍方面比淋巴瘤（4例）或推测的病毒病因（8例）更为常见。中脑和顶盖前区（8例）受累的频率与脑桥被盖部（9例）大致相同，但脑干上部病变似乎是由弓形虫病（4例）或淋巴瘤（3例）引起的，而病毒病因被认为是大多数脑干下部受累的原因。
