Roubenoff R, Kehayias J J
USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111.
Nutr Rev. 1991 Jun;49(6):163-75. doi: 10.1111/j.1753-4887.1991.tb03013.x.
Methods of measuring lean body mass have evolved greatly in the past decade. Because all practical methods of measurement are indirect (i.e., not involving carcass analysis), appropriate models of body composition must be applied. Today's improved precision is due both to better instrumentation and to improved models based on partition of the body into its constituent compartments. With this improved methodology has come the recognition that loss of lean body mass is associated with survival in starvation, acute illness, and aging. In addition, correlations of lean body mass with immune competence and functional status are beginning to emerge. It remains to be proven that changes in lean body mass in aging and disease independently determine outcome. Interventions that preserve or normalize lean body mass could be important for preservation of vigorous functional status.
在过去十年中，测量瘦体重的方法有了很大发展。由于所有实际测量方法都是间接的（即不涉及胴体分析），因此必须应用合适的身体成分模型。如今精度的提高既得益于更好的仪器设备，也得益于基于将身体划分为其组成部分的改进模型。随着这种方法的改进，人们认识到瘦体重的减少与饥饿、急性疾病和衰老过程中的生存情况相关。此外，瘦体重与免疫能力和功能状态之间的相关性也开始显现。衰老和疾病中瘦体重的变化是否能独立决定结果仍有待证明。保持或使瘦体重正常化的干预措施对于维持旺盛的功能状态可能很重要。
