Genetic Counseling Graduate Program, College of Allied Health Sciences, University of Cincinnati, Cincinnati, OH, USA.
Fam Cancer. 2010 Jun;9(2):203-12. doi: 10.1007/s10689-009-9303-3.
Telephone disclosure of BRCA1/2 molecular genetic test results has been proposed as a feasible alternative to traditional in-person results disclosure. The purpose of this study was to investigate the relationship between method of result disclosure with the patient outcome variables of knowledge, cancer worry, cancer risk perception, satisfaction, and cancer screening and prophylactic surgery behaviors. Study participants included 228 women who completed retrospective, self-administered, mailed surveys regarding their pre-test genetic counseling and results disclosure. No significant relationships were found between result disclosure method and the outcome variables investigated. A majority (90%) of individuals who received positive results by telephone returned for follow up visits. Factors which genetic counselors believed influenced their clinical decision to offer telephone disclosure, such as history of breast cancer, a priori risk of genetic mutation and family history of known mutation were not shown to significantly impact the actual disclosure method. This study suggests that telephone results disclosure is clinically appropriate when counselors utilize their clinical judgment to determine which patients are appropriate candidates.
电话告知 BRCA1/2 分子遗传学检测结果已被提议作为传统当面告知结果的一种可行替代方法。本研究旨在调查结果告知方法与患者的知识、癌症担忧、癌症风险认知、满意度以及癌症筛查和预防性手术行为等结果变量之间的关系。研究参与者包括 228 名女性，她们完成了回顾性、自我管理、邮寄的关于其预测试遗传咨询和结果告知的调查问卷。未发现结果告知方法与所调查的结果变量之间存在显著关系。大多数（90%）通过电话收到阳性结果的人返回进行随访。遗传咨询师认为影响他们提供电话告知的临床决策的因素，如乳腺癌病史、基因突变的先验风险和已知突变的家族史，并未显示出对实际告知方法有显著影响。本研究表明，当咨询师利用其临床判断确定哪些患者是合适的候选者时，电话告知结果是合理的。
