Mathan V I, Mathan M M
Wellcome Research Unit, Christian Medical College Hospital, Vellore, Tamil Nadu, India.
Rev Infect Dis. 1991 Mar-Apr;13 Suppl 4:S311-3. doi: 10.1093/clinids/13.supplement_4.s311.
Data from studies of 916 children with diarrhea, including 122 from whom shigellae were isolated, and data on patients affected in an epidemic due to Shigella dysenteriae type I were analyzed to determine whether a diagnostic clinical profile of shigellosis could be identified. Blood and/or mucus in stool, increased frequency of stool, abdominal pain, rectal tenesmus, and fever were noted more frequently in patients with shigellosis. The diagnostic confirmation of shigellosis depends on the isolation of the organism, but in the clinical situation early initiation of appropriate antibiotic therapy can be based on clinical judgment that utilizes local perceptions regarding dysentery.
对916名腹泻儿童的研究数据进行了分析，其中包括122名分离出志贺氏菌的儿童，还分析了因I型志贺氏痢疾杆菌流行而受影响患者的数据，以确定是否能识别出志贺氏菌病的诊断临床特征。志贺氏菌病患者粪便中带血和/或黏液、排便次数增加、腹痛、里急后重和发热更为常见。志贺氏菌病的诊断确认取决于病原体的分离，但在临床情况下，可根据利用当地对痢疾的认知的临床判断尽早开始适当的抗生素治疗。
