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腹腔镜与开放供体肾切除术:手术结果及术后过程评估

Laparoscopic versus open donor nephrectomy. An appraisal on surgical outcome and post-operative course.

作者信息

Iaria Maurizio, Capocasale Enzo, Dalla Valle Raffaele, Mazzoni Maria Patrizia, Sianesi Mario

机构信息

Department of Surgery, Division of Surgery and Organ Transplantation, Azienda Ospedaliero-Universitaria di Parma, Italy.

出版信息

Ann Ital Chir. 2009 Nov-Dec;80(6):449-51.

PMID:20476677
Abstract

INTRODUCTION

Laparoscopic living donor nephrectomy (LLDN) is supposed to be safe and effective and it ensures an excellent allograft function in the recipient. The use of laparoscopic technique is rapidly spreading in most transplant programs since it offers advantages over the open procedure. Aim of our study is to evaluate both surgical outcome and post-operative course in the LLDN group comparing with an historical series of open donor nephrectomies (ODN).

MATERIALS AND METHODS

From January 1992 to August 2008, 37 living donor nephrectomies were performed in our center. 23 nephrectomies were carried out, laparoscopically and 14 by open technique. Donors characteristics were comparable in both groups.

RESULTS

All laparoscopic nephrectomies were performed successfully without conversion. No significant differences were observed between the two groups for both surgical complication and graft and patient survival rates. Mean warm ischemia time (p < 0.04), resumption of oral intake (p < 0.03) and length of hospital stay (p < 0.0001) were shorter in the LLDN group. Mean operative time (p < 0.036) was longer in the LLDN group, whereas time to return to work and daily activities were similar (p < 0.52).

CONCLUSION

Laparoscopic nephrectomy provides some post-operative advantages over the open technique without additional surgical risk ensuring comparable graft and patient outcomes. Therefore, LLDN has become the standard approach in our transplant center. However, the laparoscopic procedure should be performed only by experienced surgical staff in order to prevent serious complications in the donors.

摘要

引言

腹腔镜活体供肾切除术(LLDN)被认为是安全有效的,并且能确保受者的移植肾功能良好。由于腹腔镜技术相较于开放手术具有优势,其在大多数移植项目中迅速普及。我们研究的目的是评估LLDN组的手术结果和术后病程,并与一组历史上的开放供肾切除术(ODN)进行比较。

材料与方法

1992年1月至2008年8月,我们中心共进行了37例活体供肾切除术。其中23例通过腹腔镜进行,14例采用开放技术。两组供者的特征具有可比性。

结果

所有腹腔镜肾切除术均成功完成,无一例中转开放。两组在手术并发症、移植肾及患者生存率方面均未观察到显著差异。LLDN组的平均热缺血时间(p < 0.04)、恢复经口进食时间(p < 0.03)和住院时间(p < 0.0001)均较短。LLDN组的平均手术时间较长(p < 0.036),而恢复工作和日常活动的时间相似(p < 0.52)。

结论

与开放技术相比,腹腔镜肾切除术具有一些术后优势,且无额外手术风险,移植肾及患者结局相当。因此,LLDN已成为我们移植中心的标准术式。然而,腹腔镜手术应由经验丰富的手术人员进行,以防止供者出现严重并发症。

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